IEDB Analysis Resource

MHCI Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IEDB within a single week. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.


Server Overall SRCC AUC
ANN 3.4 55 52 59
ANN 4.0 69 61 77
ARB 68 68 68
IEDB Consensus 70 75 64
NetMHCcons 65 55 75
NetMHCpan 2.8 57 55 59
NetMHCpan 3.0 63 54 73
NetMHCpan 4.0 BA 64 57 71
NetMHCpan 4.0 EL 56 50 63
NetMHCpan 4.1 BA 59 52 66
NetMHCpan 4.1 EL 39 32 46
PickPocket 56 59 54
SMM 65 73 57
SMMPMBEC 53 63 43
mhcflurry 1.2.0 54 54 55

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here.

IEDB
Reference		 Allele Peptide
Length		 Peptide
Count		 Positive
Count		 Measurement
type		 ANN 3.4 ANN 4.0 ARB IEDB Consensus NetMHCcons NetMHCpan 2.8 NetMHCpan 3.0 NetMHCpan 4.0 BA NetMHCpan 4.0 EL NetMHCpan 4.1 BA NetMHCpan 4.1 EL PickPocket SMM SMMPMBEC mhcflurry 1.2.0
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1043978   HLA-A*11:01   9   20   6   binary   0.587   0.869   0.681   0.929   0.681   0.929   0.587   0.869   0.635   0.946   0.643   0.905   0.662   0.917   0.606   0.881   0.587   0.869   0.587   0.869   -0.627   0.107   0.568   0.857   0.549   0.845   0.530   0.833   0.624   0.893 
 1043978   HLA-A*11:01   10   12   6   binary   0.869   1.000   0.869   1.000   0.871   1.000   0.871   1.000   0.869   1.000   0.869   1.000   0.869   1.000   0.869   1.000   0.579   0.833   0.869   1.000   -0.871   0.000   0.869   1.000   0.869   1.000   0.869   1.000   0.869   1.000 
 1043979   HLA-A*02:01   9   13   6   t1/2   0.388   0.643   0.435   0.714   0.591   0.738   0.749   0.810   0.388   0.667   0.485   0.690   0.513   0.738   0.614   0.786   0.586   0.881   0.524   0.738   0.469   0.810   0.700   0.810   0.764   0.833   0.630   0.762   0.416   0.667 
 1043979   HLA-A*02:01   10   12   3   t1/2   0.553   0.704   0.369   0.704   0.256   0.667   0.531   0.630   0.485   0.704   0.327   0.667   0.245   0.667   0.278   0.667   0.583   0.815   0.346   0.667   0.628   0.889   0.384   0.593   0.606   0.630   0.557   0.593   0.395   0.667