IEDB Analysis Resource
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MHCI Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IEDB within a single week. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.


Server Overall SRCC AUC
ANN 3.4 - - -
ANN 4.0 50 50 50
ARB 80 80 80
IEDB Consensus 55 55 55
NetMHCcons - - -
NetMHCpan 2.8 - - -
NetMHCpan 3.0 - - -
NetMHCpan 4.0 BA 68 68 68
NetMHCpan 4.0 EL 35 35 35
NetMHCpan 4.1 BA 74 74 74
NetMHCpan 4.1 EL 68 69 67
PickPocket 55 55 55
SMM 69 68 70
SMMPMBEC 64 64 64
mhcflurry 1.2.0 37 37 37

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here.

IEDB
Reference		 Allele Peptide
Length		 Peptide
Count		 Positive
Count		 Measurement
type		 ANN 3.4 ANN 4.0 ARB IEDB Consensus NetMHCcons NetMHCpan 2.8 NetMHCpan 3.0 NetMHCpan 4.0 BA NetMHCpan 4.0 EL NetMHCpan 4.1 BA NetMHCpan 4.1 EL PickPocket SMM SMMPMBEC mhcflurry 1.2.0
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1048198   HLA-A*02:01   9   12   10   binary   -   -   0.259   0.700   0.259   0.700   0.259   0.700   -   -   -   -   -   -   0.324   0.750   -0.065   0.450   0.324   0.750   -0.130   0.400   0.297   0.725   0.259   0.700   0.259   0.700   0.259   0.700 
 1048198   HLA-A*11:01   10   10   6   binary   -   -   -0.853   0.000   -0.647   0.125   -0.748   0.083   -   -   -   -   -   -   -0.640   0.125   0.213   0.625   -0.640   0.125   0.142   0.583   -0.642   0.125   -0.640   0.125   -0.640   0.125   -0.711   0.083 
 1048198   HLA-A*24:02   10   12   6   binary   -   -   -0.097   0.444   0.361   0.722   -0.145   0.417   -   -   -   -   -   -   -0.097   0.444   -0.339   0.306   0.000   0.500   0.267   0.681   0.127   0.556   -0.048   0.472   -0.097   0.444   -0.048   0.472 
 1048198   HLA-B*15:01   9   10   7   binary   -   -   0.114   0.571   0.114   0.571   0.114   0.571   -   -   -   -   -   -   0.114   0.571   0.038   0.524   0.114   0.571   0.418   0.762   -0.190   0.381   -   -   0.114   0.571   0.038   0.524 
 1048198   HLA-B*51:01   9   12   10   binary   -   -   -0.130   0.400   0.162   0.625   0.000   0.500   -   -   -   -   -   -   0.259   0.700   0.453   0.850   0.259   0.700   0.453   0.850   0.065   0.550   0.065   0.550   -0.130   0.400   -0.194   0.350 
 1048198   HLA-C*12:03   9   12   10   binary   -   -   -0.389   0.200   -   -   0.389   0.800   -   -   -   -   -   -   -0.389   0.200   -0.259   0.300   -0.389   0.200   0.000   0.500   0.032   0.525   0.648   1.000   0.648   1.000   -0.389   0.200