IEDB Analysis Resource

MHCI Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IEDB within a single week. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.


Server Overall SRCC AUC
ANN 3.4 50 54 46
ANN 4.0 40 37 43
ARB 27 11 43
IEDB Consensus 61 69 54
NetMHCcons 44 50 39
NetMHCpan 2.8 37 35 39
NetMHCpan 3.0 45 47 43
NetMHCpan 4.0 BA 53 59 47
NetMHCpan 4.0 EL 29 13 45
NetMHCpan 4.1 BA 66 63 69
NetMHCpan 4.1 EL 23 7 39
PickPocket 38 33 42
SMM 75 80 70
SMMPMBEC 75 78 72
mhcflurry 1.2.0 93 96 89

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here.

IEDB
Reference		 Allele Peptide
Length		 Peptide
Count		 Positive
Count		 Measurement
type		 ANN 3.4 ANN 4.0 ARB IEDB Consensus NetMHCcons NetMHCpan 2.8 NetMHCpan 3.0 NetMHCpan 4.0 BA NetMHCpan 4.0 EL NetMHCpan 4.1 BA NetMHCpan 4.1 EL PickPocket SMM SMMPMBEC mhcflurry 1.2.0
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1037887   H-2-Kd   8   22   2   ic50   0.481   0.550   0.412   0.625   -   -   0.542   0.575   0.471   0.550   0.469   0.575   0.569   0.650   0.535   0.650   0.281   0.925   0.527   0.650   0.297   0.925   0.413   0.600   0.617   0.575   0.565   0.575   0.596   0.675 
 1037887   H-2-Kd   9   38   16   ic50   0.778   0.946   0.792   0.972   0.727   0.960   0.797   0.967   0.797   0.960   0.827   0.977   0.793   0.952   0.820   0.966   0.460   0.790   0.835   0.974   0.332   0.707   0.817   0.980   0.791   0.969   0.798   0.969   0.853   0.974 
 1037887   H-2-Kd   10   34   11   ic50   0.454   0.609   0.299   0.502   0.155   0.549   0.412   0.573   0.362   0.561   0.150   0.439   0.288   0.518   0.326   0.538   0.312   0.609   0.318   0.542   0.189   0.549   0.209   0.470   0.579   0.708   0.575   0.700   0.579   0.664 
 1037887   H-2-Kd   11   38   11   ic50   0.706   0.835   0.661   0.791   -   -   0.770   0.828   0.648   0.815   0.557   0.778   0.614   0.815   0.627   0.811   0.421   0.721   0.649   0.832   0.537   0.764   0.539   0.774   0.790   0.832   0.788   0.842   0.801   0.865