IEDB Analysis Resource

MHCI Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IEDB within a single week. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.


Server Overall SRCC AUC
ANN 3.4 64 50 79
ANN 4.0 88 93 82
ARB 16 18 14
IEDB Consensus 57 68 46
NetMHCcons 61 57 64
NetMHCpan 2.8 52 54 50
NetMHCpan 3.0 75 75 75
NetMHCpan 4.0 BA 77 75 79
NetMHCpan 4.0 EL 4 4 4
NetMHCpan 4.1 BA - - -
NetMHCpan 4.1 EL - - -
PickPocket 20 18 21
SMM 34 32 36
SMMPMBEC 38 36 39
mhcflurry 1.2.0 68 68 68

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here.

IEDB
Reference		 Allele Peptide
Length		 Peptide
Count		 Positive
Count		 Measurement
type		 ANN 3.4 ANN 4.0 ARB IEDB Consensus NetMHCcons NetMHCpan 2.8 NetMHCpan 3.0 NetMHCpan 4.0 BA NetMHCpan 4.0 EL NetMHCpan 4.1 BA NetMHCpan 4.1 EL PickPocket SMM SMMPMBEC mhcflurry 1.2.0
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1033071   HLA-A*02:01   9   113   41   ic50   0.803   0.873   0.822   0.876   0.787   0.850   0.807   0.866   0.808   0.874   0.809   0.873   0.816   0.876   0.812   0.876   0.273   0.672   -   -   -   -   0.776   0.852   0.802   0.866   0.804   0.866   0.821   0.872 
 1033071   HLA-A*02:01   10   77   12   ic50   0.848   0.915   0.866   0.896   0.801   0.856   0.859   0.886   0.838   0.888   0.833   0.881   0.856   0.891   0.857   0.899   0.098   0.601   -   -   -   -   0.826   0.878   0.832   0.881   0.831   0.883   0.834   0.901