IEDB Analysis Resource

MHCI Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IED for the last at least 5 references. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Server Overall SRCC AUC
ANN 3.4 71 70 71
ANN 4.0 60 60 60
ARB 43 36 50
IEDB Consensus 54 56 53
NetMHCcons 72 69 76
NetMHCpan 2.8 72 74 70
NetMHCpan 3.0 63 59 67
NetMHCpan 4.0 BA 69 60 77
NetMHCpan 4.0 EL 46 41 51
NetMHCpan 4.1 BA 81 77 84
NetMHCpan 4.1 EL 31 27 34
PickPocket 39 40 39
SMM 48 47 49
SMMPMBEC 49 53 44
mhcflurry 1.2.0 57 59 56

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here

Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.


IEDB
Reference		 Allele Peptide
Length		 Peptide
Count		 Positive
Count		 Measurement
type		 ANN 3.4 ANN 4.0 ARB IEDB Consensus NetMHCcons NetMHCpan 2.8 NetMHCpan 3.0 NetMHCpan 4.0 BA NetMHCpan 4.0 EL NetMHCpan 4.1 BA NetMHCpan 4.1 EL PickPocket SMM SMMPMBEC mhcflurry 1.2.0
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1037895   HLA-A*02:01   9   12   8   ic50   0.692   0.750   0.643   0.656   0.643   0.719   0.677   0.703   0.664   0.719   0.692   0.719   0.497   0.656   0.587   0.719   0.182   0.500   0.692   0.719   0.126   0.469   0.503   0.562   0.657   0.688   0.699   0.688   0.790   0.781 
 1037895   HLA-A*02:01   10   11   6   ic50   0.555   0.700   0.573   0.700   0.536   0.767   0.424   0.600   0.636   0.733   0.691   0.733   0.700   0.833   0.573   0.767   0.445   0.700   0.664   0.800   0.409   0.700   0.296   0.550   0.355   0.567   0.355   0.567   0.491   0.600 
 1038020   HLA-A*02:01   9   14   6   t1/2   -0.200   0.396   -0.215   0.396   -0.163   0.458   -0.303   0.354   -0.203   0.375   -0.123   0.417   -0.010   0.479   -0.010   0.479   -0.128   0.375   -0.075   0.438   -0.195   0.312   -0.183   0.417   -0.295   0.354   -0.230   0.396   -0.198   0.417 
 1038478   HLA-A*02:01   9   25   12   binary   0.856   0.994   0.855   0.994   0.811   0.968   0.825   0.974   0.855   0.994   0.844   0.987   0.855   0.994   0.855   0.994   0.855   0.994   0.855   0.994   0.727   0.920   0.827   0.978   0.822   0.974   0.822   0.974   0.833   0.981 
 1038307   HLA-A*02:01   9   10   6   binary   0.711   0.917   0.711   0.917   0.569   0.833   0.711   0.917   0.711   0.917   0.782   0.958   0.711   0.917   0.782   0.958   0.782   0.958   0.782   0.958   0.853   1.000   0.711   0.917   0.711   0.917   0.711   0.917   0.782   0.958 
 1038759   H-2-Kb   9   12   9   binary   -0.084   0.444   -0.028   0.481   0.084   0.556   0.363   0.741   0.028   0.519   -0.084   0.444   -0.084   0.444   -0.139   0.407   -0.362   0.259   -0.084   0.444   -0.307   0.296   0.195   0.630   0.362   0.741   0.084   0.556   -0.307   0.296